Description
topoisomerase (DNA) II beta 180kDa
Location
Chromosome 3: 25,597,984-25,664,907 reverse strand.
VEGA68:CM000665.2
About this gene
This gene has 8 transcripts (splice variants), 2 orthologues and 1 paralogue.
Transcripts
| Name | Transcript ID | bp | Protein | Translation ID | Biotype | CCDS | UniProt | Flags |
|---|---|---|---|---|---|---|---|---|
| TOP2B-001 | OTTHUMT00000340821.1 | 5389 | 1621aa | OTTHUMP00000208317 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | CCDS46776 | - | |
| TOP2B-002 | OTTHUMT00000340822.2 | 3525 | 1150aa | OTTHUMP00000208318 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | - | E9PCY5 | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete |
| TOP2B-004 | OTTHUMT00000340824.2 | 3892 | No protein | - | <p>Error in the sequence in a public database (for example UniProtKB, NCBI RefSeq). Annotation is by the <a rel="external" href="http://vega.sanger.ac.uk/info/about/gene_and_transcript_types.html">VEGA/Havana</a> project.</p>Artifact | - | - | |
| TOP2B-003 | OTTHUMT00000340823.1 | 1945 | No protein | - | <p>Error in the sequence in a public database (for example UniProtKB, NCBI RefSeq). Annotation is by the <a rel="external" href="http://vega.sanger.ac.uk/info/about/gene_and_transcript_types.html">VEGA/Havana</a> project.</p>Artifact | - | - | |
| TOP2B-005 | OTTHUMT00000340825.2 | 2049 | 70aa | OTTHUMP00000209363 | Transcript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins. Nonsense mediated decay | - | H7BZ82 | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete |
| TOP2B-008 | OTTHUMT00000340828.1 | 540 | No protein | - | <p>Transcripts that don't contain an open reading frame (ORF) and cannot be placed in one of the other categories.</p>Processed transcript | - | - | |
| TOP2B-006 | OTTHUMT00000340826.1 | 584 | No protein | - | <p>Alternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.</p>Retained intron | - | - | |
| TOP2B-007 | OTTHUMT00000340827.1 | 451 | No protein | - | <p>Alternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.</p>Retained intron | - | - |
