Description
glutamate-cysteine ligase, catalytic subunit
Synonyms
GCS
Location
Chromosome 6: 53,497,341-53,616,970 reverse strand.
VEGA68:CM000668.2
About this gene
This gene has 13 transcripts (splice variants) and 2 orthologues.
Transcripts
| Name | Transcript ID | bp | Protein | Translation ID | Biotype | CCDS | UniProt | Flags |
|---|---|---|---|---|---|---|---|---|
| GCLC-001 | OTTHUMT00000359710.2 | 3813 | 637aa | OTTHUMP00000217803 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | CCDS4952 | P48506 | |
| GCLC-003 | OTTHUMT00000359948.1 | 2356 | 252aa | OTTHUMP00000217893 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | - | A0A0C4DGB2 | |
| GCLC-013 | OTTHUMT00000359973.3 | 592 | 18aa | OTTHUMP00000217907 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | - | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete |
| GCLC-006 | OTTHUMT00000359951.3 | 542 | 154aa | OTTHUMP00000217894 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | - | D6R959 | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete |
| GCLC-009 | OTTHUMT00000359954.2 | 519 | 173aa | OTTHUMP00000217897 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | - | H0Y9I7 | 5' and 3' truncations in transcript evidence prevent annotation of the start and the end of the CDS.CDS 5' and 3' incomplete |
| GCLC-010 | OTTHUMT00000359955.2 | 329 | 93aa | OTTHUMP00000217898 | <p>Genes and/or transcript that contains an open reading frame (ORF).</p>Protein coding | - | H0YAB6 | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete |
| GCLC-002 | OTTHUMT00000359947.1 | 2228 | No protein | - | <p>Error in the sequence in a public database (for example UniProtKB, NCBI RefSeq). Annotation is by the <a rel="external" href="http://vega.sanger.ac.uk/info/about/gene_and_transcript_types.html">VEGA/Havana</a> project.</p>Artifact | - | - | |
| GCLC-008 | OTTHUMT00000359953.1 | 1011 | 54aa | OTTHUMP00000217896 | Transcript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins. Nonsense mediated decay | - | D6RGF8 | |
| GCLC-007 | OTTHUMT00000359952.1 | 847 | 122aa | OTTHUMP00000217895 | Transcript is thought to undergo nonsense mediated decay, a process which detects nonsense mutations and prevents the expression of truncated or erroneous proteins. Nonsense mediated decay | - | D6REX4 | |
| GCLC-005 | OTTHUMT00000359950.1 | 3774 | No protein | - | <p>Alternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.</p>Retained intron | - | - | |
| GCLC-004 | OTTHUMT00000359949.1 | 2132 | No protein | - | <p>Alternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.</p>Retained intron | - | - | |
| GCLC-011 | OTTHUMT00000359956.1 | 776 | No protein | - | <p>Alternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.</p>Retained intron | - | - | |
| GCLC-012 | OTTHUMT00000359957.1 | 597 | No protein | - | <p>Alternatively spliced transcript that is believed to contain intronic sequence relative to other coding transcripts in a given locus.</p>Retained intron | - | - |
